小剂量受照人员远期外周血淋巴细胞染色体畸变分析

doi:10.3969/j.issn.1004-616x.1998.06.009

Abstract

Abstract: The analyses of chromosome aberrations and micronuclei in peripheral blood lymphocyte were performed in 26 cases exposed to low2dose radiation in 1966 and in 1971. The results show that the f requencies of chromosome aberration and micronucleus in the irradiated group were significantly higher than that in cont rol ( P < 0. 01) ,but a relationship between the radiation dose and the f requencies of chromosome aberrations and micronuclei was not found ; The rates of chromosome aberrations or micronuclei in the externally irradiatd group was higher than that in the internally irradiated one but the difference was not statistically significant ( P > 0. 05) . Meanwhile ,the dicent ric and t ranslocation chromosome abrerration was found only in the internally irradiated group. The results indicated that the radioactive contamination could not be removed from the body of the persons exposed to internal irradiation.

Key words: low-dose radiation, chromosome aberrration, micronucleus, late effect

Lu Yumin , Fu Baohua , Han Lin , et al. LATE OBSERVATION OF CYTOGENETICS IN PERSONS EXPOSED TO LOW2DOSE RADIATION[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1998, 10(6): 361-364.

[1]	SHI Wenjing, ZHANG Jiqianzhu, ZHU Jiangbo, ZHANG Xiaofang, WANG Ruina, DAI Xiaoyu, REN Lijun, TIAN Yijun. Evaluation of genotoxicity of diphenhydramine hydrochloride and caffeine compound [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2022, 34(2): 149-153,157.
[2]	CAI Qi, GAO Deyu, SHI Jianfeng, YU Hao, HAN Yan, YANG Liu, ZHAO Lei, WANG Zhaoxu. Potential use of tree shrew as an animal model for the micronucleus test [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(5): 370-374,382.
[3]	LU Xue, TIAN Xuelei, ZHAO Hua, CAI Tianjing, TIAN Mei, LIU Qingjie. Use of the micronucleus assay to estimate partial radiation exposure dose in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(3): 193-196.
[4]	ZHAO Hua, LU Xue, CAI Tianjing, TIAN Mei, LIU Qingjie. Effects of age and gender on formation of nucleoplasmic bridges in peripheral blood lymphocytes [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(1): 48-52.
[5]	CAO Yiyi, LIU Weiying, YOU Xinyue, XI Jing, Chen Ruixue, ZHANG Xinyu, LUAN Yang. In vitro genotoxicity evaluation of BDE-3, BDE-47 and BDE-209 [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(1): 15-20,28.
[6]	WANG Quankai, XIE Guangyun, MA Shunpeng, GUO Haoran, WUHAN Baolier, SONG Jiayang, XU Jianning. Genotoxicity evaluation of glycidyl methacrylate [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 479-482.
[7]	LI Ying, CHEN Xiaming, LI Hanrong, LUO Te. Genotoxicity of three kinds of electric mosquito repellents on plant root tip cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(5): 401-405,411.
[8]	WEN Hairuo, GUO Yajuan, HUANG Zhiying, WANG Xue, DAN Mo. Induction of cytotoxicity and DNA damage by iron oxide nanoparticles with different surface modifications in A549 cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(6): 413-421.
[9]	XIA Ying, FU Shaohua, ZHANG Yinjing, WANG Wei. Genetic toxicity test of a pesticide, Paichongding [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(2): 136-139.
[10]	CAO Yiyi, XI Jing, TANG Weifeng, YOU Xinyue, LIU Weiying, LUAN Yang. Genotoxicity evaluation of triclosan in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(1): 71-75.
[11]	WANG Zhi, LING Xi, ZHANG Guowei, GAO Jianfang, ZOU Peng, JING Che, LIN Zhetao, LIU Jinyi, CAO Jia, AO Lin. Effect of folic acid on DNA demethylation and chromosomal damage in mice after their inhalation exposure to 1, 3-butadiene [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(3): 189-193.
[12]	WANG Chao, RUAN Hongjie, DOU Jiexiong, DUAN Lian, ZHANG Hongwei. Use of the Vicia faba root tip micronucleus test to monitor the genotoxicity of tap water [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(6): 481-483,490.
[13]	WANG Chao, DUAN Lian, ZHANG Hongwei. Genetic toxicity of mercury,arsenic, formaldehyde and their combinations in Vicia faba root tip cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(5): 383-387.
[14]	HAN Tianjiao, ZHOU Changhui, CHANG Yan. Establishment a method for genotoxicity evaluation of ethyl methanesulfonate in rats using Comet and flow micronucleus assays [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(4): 277-280.
[15]	YING Jian, HAO Binxiu, MENG Qingjia, CHEN Ran, WANG Liming, WANG Chunling. Acute toxicity and genotoxicity of crude water extracts from tea mistletoe Viscum Liquidambaricolum Hayata [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(4): 306-309,324.

LATE OBSERVATION OF CYTOGENETICS IN PERSONS EXPOSED TO LOW2DOSE RADIATION

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments